Welcome to the OPEN Study website.
Older people are at increased risk of vitamin B12 deficiency which can lead to severe neurocognitive deficit (e.g. progressive weakness, vision and hearing loss, impairment in communication and co-ordination). The aim of the present study is to assess whether increased dietary intake of crystalline vitamin B12 will improve nerve function and cognitive function in older people with defined low vitamin B12 status. Demonstrating that vitamin B12 dependant nerve and cognitive function impairment is present even in individuals without clinical symptoms will have considerable public health significance.
| The OPEN study is funded by the UK Food Standards Agency |  |
Use the menu on the left to navigate around this site.
